Equation numbering (and, more generally, (cross-)references management) is not in the scope of Sage.
 What you are looking for is a document preparation system able to include and manage Sage inputs, outputs and references to them.
 One solution is Sage's SageTeX, which offers the possibility of interleaving the source of a Sage program and its results (textual, LaTeX and/or figures) with the text describing it, by post-processing the result of a first LaTeX run with a tool executing Sage snippets and inserting their source and/or results in the LaTeX source for (re-)processing. This solution, part of the standard Sage distributions, is the best for seasoned LaTeX users aiming at the preparation PDF/printed papers or presentations with their usual tools.
 I have also had some success with PythonTeX, which allows for the use of several languages (notably including R) the same way.
 The problem is more complex when aiming at preparing other types of documents, such as (X)HTML pages or (shudder...) Word or Powerpoint files (a necessity outside scientific academia...)  :
  - One possibility is to prepare LaTeX files and convert them to your desired output, for example with - pandoc, which as an astonishing range of output formats.
 
- Another one is to use a document preparation system able to generate your desired output(there are legions) and pre- or post-process it with a SageTeX-like tool (those are rare...). I have had some success with : -  - codebraid, which uses- markdownfor text input and- pandocas the processor ; supports a handful of programming languages (including- R), generates anything- pandoccan generate ;
 
- org-mode's- babeltool, which allows the insertion and execution of code written in about 70 programming languages and tools, and generate a large range of outputs (notably thanks to a clever use of- pandocin some cases) ; interestingly, this tool is a package of the (remarkable)- emacstext editor, which might be considered as a bug or as a feature, according to your taste...
 
 
- A third possibility is to use a system supporting - Pythoncode and feeding it preprocessed input, calling- from sage.all import *early in the program code. The number of text preparation system supporting- Pythonis larger than than the number of systems supporting- Sagedirectly ; I am thinking of- knitr,- rmarkdownand derived systems, aiming at supporting- Rbut able to support Python.
 
- It could be worthy to look for such tools for processing Jupyter notebooks : there exists an not-so-small cottage industry of Jupyter extensions, some of them aiming at extending its - markdownabilities...
 
I'm pretty certain that other tools, text formats and supported code languages are available somewhere on the 'Net ; what I mentioned is what I tried with at least some success. FWIW, I have used LaTeX for 35 years, but the limitations of PDF-only output made me look at other solutions ; it turns out that my current personal favorite is org-mode, probably because I have been an emacs user for 35 years...
 HTH,
 
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