I suppose you are aware that, in fact, you don't need to use solve: once defined $A$ and $Y$, the solution of the linear system $AX=Y$ is given by A\Y. For example,
 sage: A = matrix([[1,2,3], [4,5,6], [-7,8,9]])
sage: Y = vector([3,9,1])
sage: print "Solution:", A\Y
Solution: (1, 1, 0)
 Anyway, if you really need to use solve and write the system in the form $AX=Y$, you can continue the above example as follows:
 sage: X = vector([var("x_{}".format(i)) for i in [1..3]])
sage: system = [A[i]*X==Y[i] for i in range(len(Y))]
sage: solve(system, *X)
[[x_1 == 1, x_2 == 1, x_3 == 0]]
 Post-scriptum. The following function covers the cases considered in the comments below:
 def my_solve(A, Y):
    m, n = A.dimensions()
    p, q = Y.dimensions()
    if m!=p:
        raise RuntimeError("The matrices have different numbers of rows")
    X = vector([var("x_{}".format(i)) for i in [1..n]])
    sols = []
    for j in range(q):
        system = [A[i]*X==Y[i,j] for i in range(m)]
        sols += solve(system, *X)
    return sols
 Of course, A and Y should be two matrices with the same number of rows. Let us check the examples:
 sage: A = matrix(QQ, [[1, 2, 2, 2], [2, 4, 6, 8], [3, 6, 8, 10], [0, 0, 0, 0]])
sage: Y = matrix(QQ, 4, 1, [0, 0, 0, 0])
sage: my_solve(A, Y)
[[x_1 == 2*r1 - 2*r2, x_2 == r2, x_3 == -2*r1, x_4 == r1]]
 Please, note the way Y is given.
 sage: A = matrix(QQ, [[2, 4, -3], [-3, -2, 4], [2, -5, -2]])
sage: Y = matrix(QQ, [[-5, -2], [3, 1], [0, 3]])
sage: my_solve(A, Y)
[[x_1 == 51, x_2 == 4, x_3 == 41], [x_1 == -5, x_2 == -1, x_3 == -4]]
 Update. The code had an error in the way the number of unknowns was determined. I have modified the code to correct this bug. Let us check it with this new example:
 sage: A = matrix([[1, 2, 3], [5, 7, 11]])
sage: Y = matrix([[13 ,17], [19, 23]])
sage: my_solve(A, Y)
[[x_1 == -1/3*r11 - 53/3, x_2 == -4/3*r11 + 46/3, x_3 == r11],
 [x_1 == -1/3*r12 - 73/3, x_2 == -4/3*r12 + 62/3, x_3 == r12]]
 You can see these examples in this Sagemath Cell.
 
thank you for asking that. not knowing how to answer this question,(I did not dare to ask the question) I did like that but I'm sure it must be easier way ! see this post and the cocalc link in it