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Dear @ZL,

@dan_fulea's answer is right : parameterizing your expression is the rightthing to do ; and, as he wrote, this parameterization needs some hinsight in the problem you want to solve.

I just want to add that Sympy's simplify seems more agressive tn a Sage's simplifu and sometimes full simplify ; the idiom X._sympy_().simplify._sage_() might come in handy. Ditto for mathematica.FullSimplify(X).sage() (which, of course, requires Mathematica or the gratis Wolfram Engine...).

HTH,