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The simplest is probably to use scipy.optimize.minimize

sage: import scipy.optimize
sage: def f(X): 
....:     x,y = X 
....:     return 3*x^2 + 2*y^2 + x + y*cos(x*y)   
sage: res = scipy.optimize.minimize(f,(0,0))                                                              
sage: res.x                                                                                               
array([-0.16623723, -0.2493558 ])